RESTRICTION FRAGMENT LENGTH POLYMORPHISMS AT THE HUMAN PARATHYROID-HORMONE GENE LOCUS

被引：63

作者：

SCHMIDTKE, J

PAPE, B

KRENGEL, U

LANGENBECK, U

COOPER, DN

BREYEL, E

MAYER, H

机构：

[1] UNIV GOTTINGEN, INST HUMAN GENET, D-3400 GOTTINGEN, FED REP GER

[2] GESELL BIOTECHNOL FORSCH MBH, D-3300 BRUNSWICK, FED REP GER

来源：

HUMAN GENETICS | 1984年 / 67卷 / 04期

关键词：

D O I：

10.1007/BF00291404

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Two common Pst I and Taq I restriction enzyme fragment length polymorphisms (RFLP) were detected at the human parathyroid hormone (PTH) gene locus. The allele frequencies in a Northern German population were 0.578/0.422 (Pst I) and 0.628/0.372 (Taq I). The allele distributions follow Hardy-Weinberg expectations of equilibrium in the population. The Mendelian nature of the polymorphisms were confirmed in family studies.

引用

页码：428 / 431

页数：4

共 15 条

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