SUPPRESSION OF HUMAN-LYMPHOCYTE MITOGEN RESPONSE BY RETROVIRUSES OF TYPE-D .2. NON-ACTIVITY OF MASON-PFIZER MONKEY VIRUS VERSUS ACTIVITY OF HUMAN CELL-LINE DERIVED VIRUS PMFV

被引：6

作者：

DENNER, J

INDZHIIA, L

WUNDERLICH, V

SYDOW, G

BIERWOLF, D

LAPIN, BA

机构：

[1] ACAD SCI GDR, CENT INST CANC RES, DIV VIROL, DDR-1115 BERLIN, GER DEM REP

[2] ACAD MED SCI USSR, INST EXPTL PATHOL & THERAPY, MOSCOW 109801, USSR

来源：

ARCHIVES OF VIROLOGY | 1985年 / 86卷 / 3-4期

关键词：

D O I：

10.1007/BF01309824

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In contrast to the human cell line derived type D retrovirus PMFV, the Mason-Pfizer monkey virus (MPMV) does not suppress the mitogen response of normal human lymphocytes. Both viruses have been propagated on the same cell lines and purified by the same methods. MPMV did not contain a factor able to abolish PMFV-induced suppression of the mitogen response. Neither could MPMV suppress the mitogen response of lymphocytes from rhesus monkeys or baboons. PMFV however inhibited their reactivity.

引用

页码：187 / 196

页数：10

共 35 条

[1] ISOLATION OF A T-LYMPHOTROPIC RETROVIRUS FROM A PATIENT AT RISK FOR ACQUIRED IMMUNE-DEFICIENCY SYNDROME (AIDS) [J].