FUCOSYLATED GLYCOCONJUGATES IN HUMAN DORSAL-ROOT GANGLION-CELLS WITH UNMYELINATED AXONS

被引：18

作者：

KUSUNOKI, S ^{[1
]}

INOUE, K ^{[1
]}

IWAMORI, M ^{[1
]}

NAGAI, Y ^{[1
]}

MANNEN, T ^{[1
]}

机构：

[1] UNIV TOKYO,FAC MED,DEPT BIOCHEM,TOKYO 113,JAPAN

来源：

NEUROSCIENCE LETTERS | 1991年 / 126卷 / 02期

关键词：

GLYCOCONJUGATE; GANGLIOSIDE; LECTIN; DORSAL ROOT GANGLION; PERIPHERAL NERVE; IMMUNOHISTOCHEMISTRY;

D O I：

10.1016/0304-3940(91)90543-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The same subset of small neurons in human dorsal root ganglia (DRG) was recognized by both of the two probes binding to fucosylated residue, Ulex europaeus agglutinin I (UEA-1) lectin and anti-fucosyl GM1 antibody, although these probes bind to different glycoconjugates. UEA-1 lectin also bound to unmyelinated axons in DRG and in biopsied sural nerve, but not to any neurons or unmyelinated axons in the sympathetic ganglia. Thus UEA-1 lectin and anti-fucosyl GM1 antibody may be used as specific probes for primary sensory neurons with unmyelinated axons.

引用

页码：159 / 162

页数：4

共 14 条

[1] MONOCLONAL-ANTIBODIES AGAINST CARBOHYDRATE DIFFERENTIATION ANTIGENS IDENTIFY SUBSETS OF PRIMARY SENSORY NEURONS [J].