BIOSYNTHESIS OF THE POLYKETIDE POLYETHER ANTIBIOTIC ICI-139603 IN STREPTOMYCES-LONGISPOROFLAVUS FROM O-18-LABELED ACETATE AND PROPIONATE

被引：19

作者：

DEMETRIADOU, AK

LAUE, ED

STAUNTON, J

RITCHIE, GAF

DAVIES, A

DAVIES, AB

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,LENSFIELD RD,CAMBRIDGE CB2 1EW,ENGLAND

[2] ICI PLC,DIV PHARMACEUT,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1985年 / 07期

关键词：

D O I：

10.1039/c39850000408

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：408 / 410

页数：3

共 11 条

[1] BIOSYNTHESIS OF THE POLYKETIDE ANTIBIOTIC ICL139603 IN STREPTOMYCES-LONGISPOROFLAVUS - ASSIGNMENT OF THE C-13 NMR-SPECTRUM BY TWO-DIMENSIONAL METHODS, AND DETERMINATION OF THE ORIGIN OF THE CARBON-ATOMS [J].

BULSING, JM ;

LAUE, ED ;

LEEPER, FJ ;

STAUNTON, J ;

DAVIES, DH ;

RITCHIE, GAF ;

DAVIES, A ;

DAVIES, AB ;

MABELIS, RP .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1984, (19) :1301-1302

[2] MACROLIDE BIOSYNTHESIS - ORIGIN OF THE OXYGEN-ATOMS IN THE ERYTHROMYCINS [J].

CANE, DE ;

HASLER, H ;

LIANG, TC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (19) :5960-5962

[3] UNIFIED STEREOCHEMICAL MODEL OF POLYETHER ANTIBIOTIC-STRUCTURE AND BIOGENESIS [J].

CANE, DE ;

CELMER, WD ;

WESTLEY, JW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (11) :3594-3600

[4] BIOSYNTHESIS OF THE POLYETHER ANTIBIOTIC ICL139603 IN STREPTOMYCES-LONGISPOROFLAVUS - INVESTIGATION OF DEUTERIUM RETENTION AFTER INCORPORATION OF (CD3CO2H)-C-13, (CD3CO2H)-CD-13, AND (CH3CD2CO2H)-C-13 USING H-2 NMR AND EDITED-C-13 NMR-SPECTRA [J].

DODDRELL, DM ;

LAUE, ED ;

LEEPER, FJ ;

STAUNTON, J ;

DAVIES, A ;

DAVIES, AB ;

RITCHIE, GA .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1984, (19) :1302-1304

[5] NEW POLYKETIDE METABOLITES FROM ASPERGILLUS-MELLEUS - STRUCTURAL AND STEREOCHEMICAL STUDIES [J].

GARSON, MJ ;

STAUNTON, J ;

JONES, PG .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1984, (05) :1021-1026

[6] BIOSYNTHETIC-STUDIES OF MACROLIDE AND POLYETHER ANTIBIOTICS [J].

HUTCHINSON, CR .

ACCOUNTS OF CHEMICAL RESEARCH, 1983, 16 (01) :7-14

[7] MACROLIDES - RECENT PROGRESS IN CHEMISTRY AND BIOCHEMISTRY [J].

MASAMUNE, S ;

BATES, GS ;

CORCORAN, JW .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1977, 16 (09) :585-607

[8] CHEMICAL AND BIOLOGICAL STUDIES ON 16-MEMBERED MACROLIDE ANTIBIOTICS [J].

OMURA, S ;

NAKAGAWA, A .

JOURNAL OF ANTIBIOTICS, 1975, 28 (06) :401-433

[9]

Queener S W, 1978, Annu Rev Microbiol, V32, P593, DOI 10.1146/annurev.mi.32.100178.003113

[10] O-18 ISOTOPE SHIFT UPON C-13 NMR-SPECTRA AND ITS APPLICATION TO THE STUDY OF OXYGEN-EXCHANGE KINETICS [J].

RISLEY, JM ;

VANETTEN, RL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (01) :252-253

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