CLONING OF NOCARDIOFORM DNA CONFERRING THE ABILITY TO INACTIVATE RIFAMPICIN

被引：10

作者：

ANDERSEN, SJ ^{[1
]}

DABBS, ER ^{[1
]}

机构：

[1] UNIV WITWATERSRAND,DEPT GENET,PO WITS,JOHANNESBURG 2050,SOUTH AFRICA

来源：

FEMS MICROBIOLOGY LETTERS | 1991年 / 79卷 / 2-3期

关键词：

RIFAMPICIN INACTIVATION; NOCARDIOFORM; RHODOCOCCUS; DNA CLONING;

D O I：

10.1111/j.1574-6968.1991.tb04536.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A novel mechanism of resistance of rifampicin has recently been reported in which this antibiotic is inactivated. Here we describe the cloning of DNA from a nocardioform strain conferring this ability to inactivate rifampicin. Cloning was on the basis of complementation, as an increased resistance to the antibiotic. The genetic information was on a 8.3-kb Bg/II fragment.

引用

页码：247 / 250

页数：4

共 10 条

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