BRAIN ISOZYME OF GLYCOGEN-PHOSPHORYLASE - IMMUNOHISTOLOGICAL LOCALIZATION WITHIN THE CENTRAL-NERVOUS-SYSTEM

被引：66

作者：

IGNACIO, PC ^{[1
]}

BALDWIN, BA ^{[1
]}

VIJAYAN, VK ^{[1
]}

TAIT, RC ^{[1
]}

GORIN, FA ^{[1
]}

机构：

[1] UNIV CALIF DAVIS,DEPT NEUROL,NEUROSCI SECT,SURGE 3,ROOM 1161,DAVIS,CA 95616

来源：

BRAIN RESEARCH | 1990年 / 529卷 / 1-2期

关键词：

Brain isozyme; Glycogen phosphorylase; Immunohistology; Primate; Rat;

D O I：

10.1016/0006-8993(90)90809-P

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

An antibody specific for the predicted carboxyterminal sequence of the human brain isozyme of glycogen phosphorylase (α-1,4-d-glucan: orthophosphate d-glyucosyltransferase, EC 2.4.1.1) was generated to verify the carboxyterminal amino acid sequence of this protein. The isozyme-specific antibody was used to examine the localization of this protein in primate and non-primate brain. The highest levels of the brain isozyme in cerebrum and cerebellum were found in fibrous astrocytes, many with glial processes that appear to terminate upon blood vessels. © 1990.

引用

页码：42 / 49

页数：8

共 34 条

[1] EFFECTS OF EXTRACELLULAR POTASSIUM ON GLYCOGEN STORES OF ASTROCYTES INVITRO [J].

CAMBRAYDEAKIN, M ;

PEARCE, B ;

MORROW, C ;

MURPHY, S .

JOURNAL OF NEUROCHEMISTRY, 1988, 51 (06) :1846-1851

[2] EFFECTS OF NEUROTRANSMITTERS ON ASTROCYTE GLYCOGEN STORES INVITRO [J].

CAMBRAYDEAKIN, M ;

PEARCE, B ;

MORROW, C ;

MURPHY, S .

JOURNAL OF NEUROCHEMISTRY, 1988, 51 (06) :1852-1857

[3]

DAVIS CH, 1967, J BIOL CHEM, V242, P4824

[4]

DIETRICH WD, 1982, J NEUROSCI, V2, P1608

[5]

FERENDELLI J, 1971, J NEUROCHEM, V17, P1207

[6] HUMAN-BRAIN GLYCOGEN-PHOSPHORYLASE - CHARACTERIZATION OF FETAL CDNA AND GENOMIC SEQUENCES [J].

GELINAS, RP ;

FROMAN, BE ;

MCELROY, F ;

TAIT, RC ;

GORIN, FA .

MOLECULAR BRAIN RESEARCH, 1989, 6 (2-3) :177-185

[7] ABNORMAL EXPRESSION OF GLYCOGEN-PHOSPHORYLASE GENES IN REGENERATED MUSCLE [J].

GORIN, F ;

IGNACIO, P ;

GELINAS, R ;

CARLSEN, R .

AMERICAN JOURNAL OF PHYSIOLOGY, 1989, 257 (03) :C495-C503

[8] MCARDLES AND HERS DISEASES - GLYCOGEN-PHOSPHORYLASE TRANSCRIPTIONAL EXPRESSION IN HUMAN-TISSUES [J].

GORIN, FA ;

MULLINAX, RL ;

IGNACIO, PC ;

NEVE, RL ;

KURNIT, DM .

JOURNAL OF NEUROGENETICS, 1987, 4 (06) :293-308

[9] CONTROL OF GLYCOGEN-METABOLISM IN LIVER [J].

HERS, HG .

ANNUAL REVIEW OF BIOCHEMISTRY, 1976, 45 :167-189

[10]

HOF PR, 1988, J NEUROSCI, V8, P1922

← 1 2 3 4 →