ANTIMALARIAL-DRUGS .60. SYNTHESIS, ANTIMALARIAL ACTIVITY, AND QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF TEBUQUINE AND A SERIES OF RELATED 5-[(7-CHLORO-4-QUINOLINYL)AMINO]-3-[(ALKYLAMINO)METHYL][1,1'-BIPHENYL]-2-OLS AND N-OMEGA-OXIDES1,2

被引：57

作者：

WERBEL, LM

COOK, PD

ELSLAGER, EF

HUNG, JH

JOHNSON, JL

KESTEN, SJ

MCNAMARA, DJ

ORTWINE, DF

WORTH, DF

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 06期

关键词：

D O I：

10.1021/jm00156a009

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：924 / 939

页数：16

共 44 条

[1] FLUORINE-19 SUBSTITUENT CHEMICAL SHIFTS [J].

ADCOCK, W ;

BETTESS, PD ;

RIZVI, SQA .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1970, 23 (10) :1921-&

[2] ALKALOIDS OF TILIACORA RACEMOSA COLEBR [J].

ANJANEYULU, B ;

GOVINDACHARI, TR ;

SATHE, SS ;

VISWANATHAN, N ;

PAI, BR .

TETRAHEDRON, 1969, 25 (15) :3091-+

[3] MECHANISM OF ANTIMALARIAL ACTIVITY OF CHLOROQUINE ANALOGS FROM QUANTITATIVE STRUCTURE-ACTIVITY STUDIES - FREE ENERGY RELATED MODEL [J].

BASS, GE ;

HUDSON, DR ;

PARKER, JE ;

PURCELL, WP .

JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (04) :275-&

[4]

BINOVIC K, 1968, Chimica Therapeutica, V3, P313

[5]

BROOKE GM, 1968, TETRAHEDRON LETT, P2029

[6] AMINOALKYLPHENOLS AS ANTIMALARIALS .1. SIMPLY SUBSTITUTED ALPHA-AMINOCRESOLS [J].

BURCKHALTER, JH ;

TENDICK, FH ;

JONES, EM ;

HOLCOMB, WF ;

RAWLINS, AL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1946, 68 (10) :1894-1901

[7] AMINOALKYLPHENOLS AS ANTIMALARIALS .2. (HETEROCYCLIC-AMINO)-ALPHA-AMINO-O-CRESOLS - THE SYNTHESIS OF CAMOQUIN [J].

BURCKHALTER, JH ;

TENDICK, FH ;

JONES, EM ;

JONES, PA ;

HOLCOMB, WF ;

RAWLINS, AL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1948, 70 (04) :1363-1373

[8] NEW SYNTHESIS OF ALPHA-(2-PYRIDYL)KETONES BY ACYLATION OF 2-PICOLYLLITHIUM AND 2,6-LUTIDYLLITHIUM WITH N,N-DIMETHYLCARBOXAMIDES [J].

CASSITY, RP ;

TAYLOR, LT ;

WOLFE, JF .

JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (11) :2286-2288

[9] THE EFFECT OF SUBSTITUENT GROUPS UPON THE COURSE OF THE CONDENSATION REACTION BETWEEN BENZENEDIAZONIUM SALTS AND PHENOLS [J].

COLBERT, JC ;

LACY, RM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1946, 68 (02) :270-271

[10]

Dakin HD, 1928, J BIOL CHEM, V78, P757

← 1 2 3 4 5 →