CATALYTIC MECHANISM OF CYTOCHROME-P-450 - EVIDENCE FOR A DISTAL CHARGE RELAY

[1] DEUTERIUM-ISOTOPE EFFECTS IN NORCAMPHOR METABOLISM BY CYTOCHROME-P-450CAM - KINETIC EVIDENCE FOR THE 2-ELECTRON REDUCTION OF A HIGH-VALENT IRON OXO INTERMEDIATE [J]. BIOCHEMISTRY, 1988, 27 (05) : 1610 - 1616

[2] COULSON AFW, 1971, J BIOL CHEM, V246, P917

[3] PROBING STRUCTURE-FUNCTION RELATIONS IN HEME-CONTAINING OXYGENASES AND PEROXIDASES [J]. SCIENCE, 1988, 240 (4851) : 433 - 439

[4] ALIPHATIC HYDROXYLATION VIA OXYGEN REBOUND - OXYGEN-TRANSFER CATALYZED BY IRON [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (03) : 859 - 861

[5] ALIPHATIC HYDROXYLATION BY HIGHLY PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450 - EVIDENCE FOR A CARBON RADICAL INTERMEDIATE [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 81 (01) : 154 - 160

[6] GUENGERICH FP, 1990, ASIA PAC J PHARMACOL, V5, P253

[7] UNCOUPLING OF THE CYTOCHROME P-450CAM MONOOXYGENASE REACTION BY A SINGLE MUTATION, THREONINE-252 TO ALANINE OR VALINE - A POSSIBLE ROLE OF THE HYDROXY AMINO-ACID IN OXYGEN ACTIVATION [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (20) : 7823 - 7827

[8] MAPPING DETERMINANTS OF THE SUBSTRATE SELECTIVITIES OF P450 ENZYMES BY SITE-DIRECTED MUTAGENESIS [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 1992, 13 (03) : 122 - 126

[9] ALTERATION OF THE CYTOCHROME-C-OXIDASE SUBUNIT-2 GENE IN THE [EXN-5] MUTANT OF NEUROSPORA-CRASSA [J]. CURRENT GENETICS, 1991, 20 (1-2) : 121 - 127

[10] A CONSERVED RESIDUE OF CYTOCHROME-P-450 IS INVOLVED IN HEME-OXYGEN STABILITY AND ACTIVATION [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (26) : 9252 - 9253

[1] DEUTERIUM-ISOTOPE EFFECTS IN NORCAMPHOR METABOLISM BY CYTOCHROME-P-450CAM - KINETIC EVIDENCE FOR THE 2-ELECTRON REDUCTION OF A HIGH-VALENT IRON OXO INTERMEDIATE [J]. BIOCHEMISTRY, 1988, 27 (05) : 1610 - 1616

[2] COULSON AFW, 1971, J BIOL CHEM, V246, P917

[3] PROBING STRUCTURE-FUNCTION RELATIONS IN HEME-CONTAINING OXYGENASES AND PEROXIDASES [J]. SCIENCE, 1988, 240 (4851) : 433 - 439

[4] ALIPHATIC HYDROXYLATION VIA OXYGEN REBOUND - OXYGEN-TRANSFER CATALYZED BY IRON [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (03) : 859 - 861

[5] ALIPHATIC HYDROXYLATION BY HIGHLY PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450 - EVIDENCE FOR A CARBON RADICAL INTERMEDIATE [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 81 (01) : 154 - 160

[6] GUENGERICH FP, 1990, ASIA PAC J PHARMACOL, V5, P253

[7] UNCOUPLING OF THE CYTOCHROME P-450CAM MONOOXYGENASE REACTION BY A SINGLE MUTATION, THREONINE-252 TO ALANINE OR VALINE - A POSSIBLE ROLE OF THE HYDROXY AMINO-ACID IN OXYGEN ACTIVATION [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (20) : 7823 - 7827

[8] MAPPING DETERMINANTS OF THE SUBSTRATE SELECTIVITIES OF P450 ENZYMES BY SITE-DIRECTED MUTAGENESIS [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 1992, 13 (03) : 122 - 126

[9] ALTERATION OF THE CYTOCHROME-C-OXIDASE SUBUNIT-2 GENE IN THE [EXN-5] MUTANT OF NEUROSPORA-CRASSA [J]. CURRENT GENETICS, 1991, 20 (1-2) : 121 - 127

[10] A CONSERVED RESIDUE OF CYTOCHROME-P-450 IS INVOLVED IN HEME-OXYGEN STABILITY AND ACTIVATION [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (26) : 9252 - 9253