SERUM FATTY-ACID PROFILES IN CYSTIC-FIBROSIS PATIENTS AND THEIR PARENTS

被引：37

作者：

CHRISTOPHE, AB

WARWICK, WJ

HOLMAN, RT

机构：

[1] UNIV MINNESOTA,HORMEL INST,AUSTIN,MN 55912

[2] STATE UNIV GHENT,DEPT ENDOCRINOL & MET DIS,DIV NUTR,B-9000 GHENT,BELGIUM

[3] UNIV MINNESOTA HOSP,CYST FIBROSIS RES CTR,MINNEAPOLIS,MN 55455

来源：

LIPIDS | 1994年 / 29卷 / 08期

关键词：

D O I：

10.1007/BF02536629

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fatty acid compositions of the major serum lipid classes from 43 cystic fibrosis (CF) homozygotes (CF patients), 36 obligate heterozygotes (parents of CF patients) and 34 controls were determined by capillary gas chromatography. Fatty acid compositions of the homozygote CF patients were skewed in the direction of relative essential fatty acid deficiency in comparison with the controls. Less pronounced, but similar deviations from normal, were observed in the heterozygotes. Homozygotes with normal fatty acid compositions and heterozygotes with considerably disturbed fatty acid profiles were found.

引用

页码：569 / 575

页数：7

共 44 条

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