NUCLEAR AND CYTOPLASMIC LOCATION OF THE FER TYROSINE KINASE

被引:57
作者
HAO, QL
FERRIS, DK
WHITE, G
HEISTERKAMP, N
GROFFEN, J
机构
[1] CHILDRENS HOSP LOS ANGELES,DEPT PATHOL,MOLEC DIAGNOSIS SECT,4650 SUNSET BLVD,LOS ANGELES,CA 90027
[2] NCI,FREDERICK CANC RES & DEV CTR,PROGRAM RESOURCES INC,FREDERICK,MD 21701
关键词
D O I
10.1128/MCB.11.2.1180
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The location of the FER protein within the cell was investigated by using subcellular fractionation and immunofluorescence. FER was found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes.
引用
收藏
页码:1180 / 1183
页数:4
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