BLEOMYCIN INCREASES AMIKACIN AND STREPTOMYCIN RESISTANCE IN ESCHERICHIA-COLI HARBORING TRANSPOSON TN5

被引：5

作者：

BLAZQUEZ, J ^{[1
]}

MARTINEZ, JL ^{[1
]}

BAQUERO, F ^{[1
]}

机构：

[1] UAM, FAC MED, DEPT BIOQUIM, CSIC, CTR INVEST BIOMED, E-28029 MADRID, SPAIN

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 09期

关键词：

D O I：

10.1128/AAC.37.9.1982

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

The antitumor antibiotic bleomycin acts as a transcriptional inducer of the neo-ble-str operon of the transposon Tn5, increasing the resistance level to streptomycin and amikacin in Tn5-containing Escherichia coli. The mechanism may involve a recA-independent induction mediated by DNA damage.

引用

页码：1982 / 1985

页数：4

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