INVITRO ACTIVITY OF AZITHROMYCIN AGAINST CLINICAL ISOLATES OF LEGIONELLA SPECIES

被引:72
作者
EDELSTEIN, PH [1 ]
EDELSTEIN, MAC [1 ]
机构
[1] UNIV PENN,SCH MED,DEPT MED,PHILADELPHIA,PA 19104
关键词
D O I
10.1128/AAC.35.1.180
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The activities of azithromycin, erythromycin, and ciprofloxacin against 21 Legionella isolates were measured by an agar dilution method and in macrophages. The MICs for 90% of strains tested were 2.0, 1.0, and 0.5-mu-g/ml for azithromycin, erythromycin, and ciprofloxacin, respectively. Azithromycin and ciprofloxacin were both bactericidal in the macrophage system, but erythromycin was bacteriostatic.
引用
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页码:180 / 181
页数:2
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