CONTINUOUS MONITORING OF UREA IN BLOOD DURING DIALYSIS

被引：44

作者：

THAVARUNGKUL, P ^{[1
]}

HAKANSON, H ^{[1
]}

HOLST, O ^{[1
]}

MATTIASSON, B ^{[1
]}

机构：

[1] UNIV LUND,CTR CHEM,DEPT BIOTECHNOL,POB 124,S-22100 LUND,SWEDEN

来源：

BIOSENSORS & BIOELECTRONICS | 1991年 / 6卷 / 02期

关键词：

UREA; UREASE; SAMPLING; IMMOBILIZED; CONDUCTIVITY; BLOOD;

D O I：

10.1016/0956-5663(91)87033-8

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Urease was immobilized to porous glass and used in combination with a conductivity meter for determining urea in standard solutions as well as in blood from a patient undergoing dialysis. The sampling unit involves a possibility for heparinization at the sampling point and a dialysis step prior to exposure to the enzyme column. The unit operates in a linear mode in the concentration range 5-50 mM. Monitoring of the dialysis process gave good correlation with off-line analyses.

引用

页码：101 / 107

页数：7

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