ROLE OF TECHNETIUM 99M METHOXYISOBUTYLISONITRILE SINGLE PHOTON-EMISSION TOMOGRAPHY IN THE EVALUATION OF THROMBOLYSIS IN ACUTE MYOCARDIAL-INFARCTION BEFORE AND AFTER ADMISSION TO HOSPITAL

被引：6

作者：

FARAGGI, M

BOK, B

机构：

[1] HOSP A BECLERE,CLAMART,FRANCE

[2] HOSP LARIBOISIERE,PARIS,FRANCE

[3] BRIGADE SAPEURS POMPIERS PARIS,SERV MED URGENCE,PARIS,FRANCE

[4] HOSP X BICHAT,PARIS,FRANCE

[5] BRIGADE SAPEURS POMPIERS PARIS,SERV MOBILE URGENCE & REANIMAT HAUTS SEINE 92,PARIS,FRANCE

[6] HOP BEAUJON,DEPT CARDIOL,F-92110 CLICHY,FRANCE

来源：

EUROPEAN JOURNAL OF NUCLEAR MEDICINE | 1991年 / 18卷 / 02期

关键词：

METHOXYISOBUTYLISONITRILE SINGLE PHOTON EMISSION TOMOGRAPHY; ACUTE MYOCARDIAL INFARCTION; AT HOME THROMBOLYSIS; MYOCARDIAL SALVAGE;

D O I：

10.1007/BF00950753

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

To investigate initial perfusion status in acute myocardial infarction, methoxyisobutylisonitrile (MIBI) was administered by the rescue physicians. Thirty-nine patients received the radiopharmaceutical at home or upon arrival at the hospital. Diagnosis was confirmed in 30 patients, and 19 emergency thrombolyses were performed. Initial single photon emission tomography (SPET) analysis was constantly abnormal in confirmed myocardial infarction sometimes before direct electrocardiographic signs. MIBI-SPET was normal in non-coronary syndromes. MIBI uptake improved after thrombolysis (P < 0.001) but also after heparin therapy (P < 0.05). SPET improvement demonstrated myocardial salvage earlier than wall motion studies. MIBI administration at the patient's home allowed very early perfusion imaging when thrombolysis was performed at home. MIBI-SPET has the potential use of comparing thrombolytic agents or at home versus in hospital thrombolysis.

引用

页码：91 / 98

页数：8

共 19 条

[1]

[Anonymous], 1986, Lancet, V1, P397

[2] ROLE OF MYOCARDIAL PERFUSION IMAGING IN EVALUATING THROMBOLYTIC THERAPY FOR ACUTE MYOCARDIAL-INFARCTION [J].