INTRAGASTRIC PH PATTERN-ANALYSIS IN PATIENTS WITH DUODENOGASTRIC REFLUX

被引:4
作者
FUCHS, KH
DEMEESTER, TR
机构
[1] Department of General Surgery, University of Kiel
[2] Department of Surgery, Creighton University, Omaha, NE
关键词
Discriminant analysis; Duodenogastric reflux; pH monitoring; 24-hour intragastric;
D O I
10.1159/000171280
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The intention of the present study was to apply 24-hour intragastric pH monitoring as a diagnostic tool for the detection of pathologic duodenogastric reflux. Therefore. an evaluation system was developed which is able to recognize and quantify specific intraluminal gastric pH patterns regarding their specificity for the disease. pH parameters, stored during 24 h and processed, according to the evaluation system, were obtained for a healthy control population (n = 30) and for patients with pathologic duodenogastric reflux (n = 11). These data were subjected to computerized discriminant analysis to identify pH changes with a high probability of resulting from pathologic duodenogastric reflux. The computer analysis identified 16 discriminating pH parameters to separate a physiologic pH pattern from a 24-hour intragastric pH pattern with a high probability of being associated with pathologic duodenogastric reflux. © 1990 S. Karger AG, Basel.
引用
收藏
页码:54 / 59
页数:6
相关论文
共 13 条
[1]  
Little A.G., DeMecster T.R., Skinner D.B., Combined gastric and esophageal 24-hour pH monitoring in patients with gastroesophageal reflux, Surg Forum, 30, pp. 351-352, (1979)
[2]  
DeMeester T.R., Limitations of 24-hour pH monitoring, Oesophageal Disorders, pp. 109-117, (1985)
[3]  
Del Genio A., Fei L., Di Martino N., Maffettonie V., Experience with combined esophagogastric monitoring, Oesophageal Disorders, pp. 621-633, (1985)
[4]  
Emde C., Garner A., Blum A.L., Technical aspects of intraluminal pH-metry in man: Current status and recommendations, Gut, 28, pp. 1177-1188, (1987)
[5]  
Toye D., Alexander Williams J.A., Postgastrectomy bile vomiting, Lancet, 1, pp. 524-526, (1965)
[6]  
Ritchie W.P., Alkaline reflux gastritis: An objective assessment of its diagnosis and treatment, Ann Surg, 92, pp. 288-298, (1980)
[7]  
Ritchie W.P., Alkaline reflux gastritis: A critical reappraisal, Gut, 25, pp. 975-987, (1984)
[8]  
Etienne A., Fimmel C.J., Bron B.A., Loizeau E., Blum A.L., Evaluation of pircnzipine on gastric acidity in healthy volunteers using ambulatory 24-hours intragastric pH-metry, Gut, 26, pp. 241-245, (1985)
[9]  
Fimmel C.J., Etienne A., Cilluffo T., Long-term ambulatory gastric pH monitoring: Validation of a new method and effect of H2-receptor antagonists, Gastroenterology, 88, pp. 1842-1851, (1985)
[10]  
Merki H., Witzel L., Harre K., Circadian pattern of intragastric acidity in duodenal ulcer patients. A comparison with healthy controls, Gastroenterology, 90, (1986)