THE CORRELATION OF PASSIVE-AVOIDANCE DEFICIT IN AGED RAT WITH THE LOSS OF NUCLEUS BASALIS CHOLINE ACETYLTRANSFERASE-POSITIVE NEURONS

被引：25

作者：

RIEKKINEN, P ^{[1
]}

MIETTINEN, R ^{[1
]}

SIRVIO, J ^{[1
]}

AALTONEN, M ^{[1
]}

RIEKKINEN, P ^{[1
]}

机构：

[1] UNIV KUOPIO,DEPT PATHOL,SF-70211 KUOPIO,FINLAND

来源：

BRAIN RESEARCH BULLETIN | 1990年 / 25卷 / 03期

关键词：

Ageing; Choline acetyltransferase; Correlation; Nucleus basalis; Passive avoidance deficit;

D O I：

10.1016/0361-9230(90)90230-W

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The present study investigates the effects of ageing on the number of choline acetyltransferase (ChAT)-positive neurons in the nucleus basalis (NB) and the correlation between the number of ChAT-positive neurons and passive avoidance (PA) retention in young (3-month-old) and aged (26-month-old) rats. The results indicate that the number of ChAT-positive neurons is decreased in aged rats and that the degree of loss of NB neurons is related to the degree of PA retention deficit in aged rats. © 1990.

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页码：415 / 417

页数：3

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