GUT INTRAEPITHELIAL LYMPHOCYTES AND GASTROINTESTINAL-DISEASES

被引：25

作者：

CERFBENSUSSAN, N

CERF, M

GUYGRAND, D

机构：

[1] INSERM U 132, Hopital Necker-Enfants Malades, Pavillion Kirmisson, 75743 Paris Cedex 15

来源：

CURRENT OPINION IN GASTROENTEROLOGY | 1993年 / 9卷 / 06期

关键词：

D O I：

10.1097/00001574-199309060-00011

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

intraepithelial lymphocytes interspersed between intestinal epithelial cells form a large population of T cells, mainly CD8+, close to the intestinal lumen. Together with lamina propria T cells and plasma cells, they represent the effector limb of the gut-associated lymphoid system. Recent data highlighting their original properties and their interactions with epithelial cells are reviewed; their contributions to immune defenses and gastrointestinal diseases in humans are discussed.

引用

页码：953 / 961

页数：9