CYCLIC AMP-DEPENDENT STIMULATION OF SOMATOSTATIN SECRETION BY ISOLATED RAT ISLETS OF LANGERHANS

被引：48

作者：

BARDEN, N ^{[1
]}

ALVARADOURBINA, G ^{[1
]}

COTE, JP ^{[1
]}

DUPONT, A ^{[1
]}

机构：

[1] UNIV LAVAL, CTR HOSP, MRC MOLEC ENDOCRINOL GRP, QUEBEC CITY 10, QUEBEC, CANADA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1976年 / 71卷 / 03期

关键词：

D O I：

10.1016/0006-291X(76)90907-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Immunoreactive somatostatin is released from islets of Langerhans, isolated from rat pancreas by collagenase digestion, when incubated in an in vitro system. The rate of somatostatin secretion is independent of extracellular glucose concentration but is stimulated by addition of 8-bromo-cyclic AMP or theophylline.

引用

页码：840 / 844

页数：5

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