PAYNE-LIKE REARRANGEMENT OF N-TOSYL-OXIRANEMETHYLAMINES - A NEW ROUTE TO FUNCTIONALIZED AZIRIDINES

被引：23

作者：

MOULINES, J ^{[1
]}

CHARPENTIER, P ^{[1
]}

BATS, JP ^{[1
]}

NUHRICH, A ^{[1
]}

LAMIDEY, AM ^{[1
]}

机构：

[1] UNIV BORDEAUX 2,CHIM THERAPEUT LAB,UFR SCI PHARMACEUT,F-33076 BORDEAUX,FRANCE

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 04期

关键词：

D O I：

10.1016/S0040-4039(00)93976-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of N-tosyl-oxiranemethylamines with aqueous sodium hydroxide affords N-tosyl-aziridinemethanols in excellent yields, through the intramolecular epoxide ring opening by the nitrogen atom of the tosylamino group.

引用

页码：487 / 490

页数：4

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