ANTIMALARIAL ACTIVITY OF N-HENTRIACONTANOL ISOLATED FROM CUATRESIA SP (SOLANACEAE)

被引：7

作者：

DEHARO, E ^{[1
]}

SAUVAIN, M ^{[1
]}

MORETTI, C ^{[1
]}

RICHARD, B ^{[1
]}

RUIZ, E ^{[1
]}

MASSIOT, G ^{[1
]}

机构：

[1] FAC PHARM REIMS,PHARMACOGNOSIE LAB,CNRS,URA 492,F-51096 REIMS,FRANCE

来源：

ANNALES DE PARASITOLOGIE HUMAINE ET COMPAREE | 1992年 / 67卷 / 04期

关键词：

ANTIMALARIAL; INVIVO; PLASMODIUM-VINCKEI; BERGHEI; N-HENTRIACONTANOL; CUATRESIA; SOLANACEAE;

D O I：

10.1051/parasite/1992674126

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The antimalarial activity of the fatty alcool, n-hentriacontanol, isolated from the bolivian Solanaceae, Cuatresia sp, is investigated in vivo through a classical four-day suppressive test against Plasmodium berghei and P. vinckei in mice. This product markedly reduced the virulence of experimentally induced P. vinckei infection. n-Hentriacontanol belongs to a new class of antimalarial natural compounds to be exploited for therapeutic purposes.

引用

页码：126 / 127

页数：2

共 7 条

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