PRODUCTION OF PARALYTIC SHELLFISH TOXINS BY A BACTERIUM MORAXELLA SP ISOLATED FROM PROTOGONYAULAX-TAMARENSIS

被引：58

作者：

KODAMA, M ^{[1
]}

OGATA, T ^{[1
]}

SAKAMOTO, S ^{[1
]}

SATO, S ^{[1
]}

HONDA, T ^{[1
]}

MIWATANI, T ^{[1
]}

机构：

[1] OSAKA UNIV,MICROBIAL DIS RES INST,DEPT BACTERIOL & SEROL,SUITA,OSAKA 565,JAPAN

来源：

TOXICON | 1990年 / 28卷 / 06期

关键词：

D O I：

10.1016/0041-0101(90)90259-A

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A bacterium Moraxella sp. isolated from Protogonyaulax tamarensis was cultured in various conditions. Changes of toxicity and toxin components of the cells during culture were analyzed by bioassay and HPLC-fluorometric analysis. Toxin productivity of Moraxella sp. increased when it was cultured in nutrition-deficient environments. The main toxins produced by Moraxella sp. in these conditions were gonyautoxins (GTXs), mainly GTX 1 and 4 which are major toxins of P. tamarensis. © 1990.

引用

页码：707 / 714

页数：8

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