RESOLUTION OF TERNARY MIXTURES OF NITROFURANTOIN, FURAZOLIDONE AND FURALTADONE BY APPLICATION OF PARTIAL LEAST-SQUARES ANALYSIS TO THE DIFFERENTIAL-PULSE POLAROGRAPHIC SIGNALS

The abilities of the Partial Least Squares (PLS) methods in the resolution of ternary mixtures of organic compounds (furaltadone, furazolidone and nitrofurantoin) by using their differential pulse polarographic (DPP) signals are reported. The applicability of these methods to resolve very overlapped peaks whose Ep also changes with concentration is demonstrated. The analysis of both synthetic and real samples has been made with satisfactory results. The relative error or prediction (REP) is 8.7% for FD, 7.7% for FZ and 6.7% for NF by application of the PLS-2 method.