A NOVEL TYPE OF DIMERIC SECOIRIDOID GLYCOSIDE FROM LISIANTHIUS-JEFENSIS ROBYNS ET ELIAS

被引：18

作者：

HAMBURGER, M

HOSTETTMANN, M

STOECKLIEVANS, H

SOLIS, PN

GUPTA, MP

HOSTETTMANN, K

机构：

[1] UNIV LAUSANNE, ECOLE PHARM, INST PHARMACOGNOSIE & PHYTOCHIM, 2 RUE VUILLERMET, CH-1005 LAUSANNE, SWITZERLAND

[2] UNIV PANAMA, FAC FARM, UNIDAD INVEST FARMACOGNOS, PANAMA CITY, PANAMA

[3] UNIV PANAMA, INST ESPECIALIZADO ANAL, PANAMA CITY, PANAMA

[4] UNIV NEUCHATEL, INST CHIM, CH-2000 NEUCHATEL, SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1990年 / 73卷 / 07期

关键词：

D O I：

10.1002/hlca.19900730706

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A dimeric secoiridoid glucoside named lisianthioside (l) has been isolated from the roots of Lisianthius jefensis ROBYNS et ELIAS (Gentianaceae). The structure was established by spectroscopic analysis (UV, IR, 1H‐ and 13C‐NMR, DCI‐MS) of glycoside 1, peracetate 1a, aglycone 3 and the dimethoxy derivatives 4a–c. Lisianthioside (1) is the first representative of a novel type of dimeric secoiridoids. Biogenetically derived from two sweroside (2) moieties, the tricyclic aglycone features a symmetrical 12‐membered bislactone ring. In contrast to the moderately bitter sweroside (2), lisianthioside (1) is tasteless. Copyright © 1990 Verlag GmbH & Co. KGaA, Weinheim

引用

页码：1845 / 1852

页数：8

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