THE TERT-BUTYL SULFOXIDE DIRECTED ORTHO-METALATION GROUP - NEW SYNTHETIC METHODOLOGY FOR SUBSTITUTED AROMATICS AND PYRIDINES AND COMPARISON WITH OTHER METALATION DIRECTORS

被引：54

作者：

QUESNELLE, C ^{[1
]}

IIHAMA, T ^{[1
]}

AUBERT, T ^{[1
]}

PERRIER, H ^{[1
]}

SNIECKUS, V ^{[1
]}

机构：

[1] UNIV WATERLOO,GUELPH WATERLOO CTR GRAD WORK CHEM,WATERLOO N2L 3G1,ONTARIO,CANADA

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(00)79042-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Details of the directed ortho metalation of tert-butyl phenyl sulfoxide (1) and 2- and 4-tert-butyl pyridyl sulfoxides (3a,b) are described along with comparisons with established metalation directors (CONR2, OCONR2, OMOM, SO2t-Bu) via inter- and intramolecular competition experiments.

引用

页码：2625 / 2628

页数：4

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