QUANTITATION OF LATENT VARICELLA-ZOSTER VIRUS-DNA IN HUMAN TRIGEMINAL GANGLIA BY POLYMERASE CHAIN-REACTION

被引：50

作者：

MAHALINGAM, R

WELLISH, M

LEDERER, D

FORGHANI, B

COHRS, R

GILDEN, D

机构：

[1] UNIV COLORADO,SCH MED,DEPT MICROBIOL,DENVER,CO 80262

[2] CALIF DEPT HLTH SERV,DIV LABS,VIRAL & RICKETTSIAL DIS LAB,BERKELEY,CA 94704

来源：

JOURNAL OF VIROLOGY | 1993年 / 67卷 / 04期

关键词：

D O I：

10.1128/JVI.67.4.2381-2384.1993

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Competitive polymerase chain reaction was used to quantitate latent varicella-zoster virus (VZV) DNA in human trigeminal ganglia. Ganglionic DNA from five subjects was amplified with oligonucleotide primers specific for VZV gene 28. Two of the samples were also analyzed with primers specific for VZV gene 62. Our results indicated that there are 6 to 31 copies of the VZV genome in every 100,000 ganglionic cells.

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页码：2381 / 2384

页数：4

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