SYNTHESIS OF AZAPYRANOSYL THIOGLYCOSIDE - NOVEL PSEUDO-DISACCHARIDE HAVING AN AZASUGAR RESIDUE AT THE NONREDUCING END

被引：31

作者：

SUZUKI, K ^{[1
]}

HASHIMOTO, H ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,FAC BIOSCI & BIOTECHNOL,DEPT LIFE SCI,YOKOHAMA 227,JAPAN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 24期

关键词：

D O I：

10.1016/S0040-4039(00)73128-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first synthesis of azapyranosyl pseudo-disaccharide was described. Glycosidation of N-Boc-5-amino-5-deoxy-D-arabinose with N-acetyl-6-thio-D-glucosaminide in the presence of TsOH gave the corresponding 1,2-cis linked thioglycoside exclusively. The interglycosidic linkage was proved to be stable enough for the deprotection of N-Boc group by TFA.

引用

页码：4119 / 4122

页数：4

共 13 条

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