DIAGNOSIS OF CEREBROVASCULAR-DISEASE IN SICKLE-CELL-ANEMIA BY MAGNETIC-RESONANCE ANGIOGRAPHY

被引：51

作者：

WIZNITZER, M ^{[1
]}

RUGGIERI, PM ^{[1
]}

MASARYK, TJ ^{[1
]}

ROSS, JS ^{[1
]}

MODIC, MT ^{[1
]}

BERMAN, B ^{[1
]}

机构：

[1] CASE WESTERN RESERVE UNIV, SCH MED, DEPT PEDIAT & RADIOL, CLEVELAND, OH 44106 USA

来源：

JOURNAL OF PEDIATRICS | 1990年 / 117卷 / 04期

关键词：

D O I：

10.1016/S0022-3476(05)80687-0

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The study of blood flow by means of magnetic resonance techniques has led to a noninvasive magnetic resonance angiography (MRA) technique for imaging large cerebral vessles. Ten children with sickle cell hemoglobinopathy and a history of acute neurologic syndromes were studied with combined parenchymal magnetic resonance imaging (MRI) and MRA. Six had abnormal MRI findings and MRA-defined luminal lesions in the vascular distribution of these parenchymal infarctions. The three children with previous intraarterial angiography had MRA abnormalities that corresponded with vascular lesions on conventional angiograms. Four had normal MRI and MRA findings. We conclude that a combination of MRI and MRA provides a noninvasive screening test for large-vessel disease in this population. © 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：551 / 555

页数：5

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