IS THE PHARMACOLOGICAL TREATMENT OF CANCER CACHEXIA POSSIBLE

被引:12
作者
BRUERA, E
机构
[1] Palliative Care Program, Edmonton General Hospital, Edmonton, T5K 0L4, Alberta
关键词
CANCER CACHEXIA; NUTRITION; ANOREXIA;
D O I
10.1007/BF00364967
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cancer cachexia is highly prevalent in patients with advanced cancer. Its main clinical manifestation is profound anorexia. Progestational drugs have shown meaningful effects on appetite, food intake, and nutritional status in patients with advanced cancer and AIDS, and could be useful in managing anorexia. Corticosteroids also seem to produce increased appetite, but these effects are short-lived. Cyproheptadine, hydrazine sulfate, and cannabinoids also are being studied in the management of cancer-induced anorexia, but their role has not yet been clearly established. Future research should evaluate how the different drugs affect specific symptoms associated with cachexia.
引用
收藏
页码:298 / 304
页数:7
相关论文
共 64 条
[1]  
AISNER J, 1990, SEMIN ONCOL, V17, P2
[2]  
BLACKBURN G, 1985, ONCOLOGY, P1406
[3]  
BRENNAN MF, 1985, CANCER PRINCIPLES PR, P1907
[4]  
BRUERA E, 1990, CANCER, V66, P1279, DOI 10.1002/1097-0142(19900915)66:6&lt
[5]  
1279::AID-CNCR2820660630&gt
[6]  
3.0.CO
[7]  
2-R
[8]  
Bruera E, 1990, J Pain Symptom Manage, V5, P218, DOI 10.1016/0885-3924(90)90014-B
[9]  
BRUERA E, 1985, CANCER TREAT REP, V69, P751
[10]  
Bruera E, 1988, J Pain Symptom Manage, V3, P133, DOI 10.1016/0885-3924(88)90158-3