MAXIMUM-LIKELIHOOD MODELS FOR MAPPING GENETIC-MARKERS SHOWING SEGREGATION DISTORTION .1. BACKCROSS POPULATIONS

被引:125
作者
LORIEUX, M
GOFFINET, B
PERRIER, X
DELEON, DG
LANAUD, C
机构
[1] INRA,BIOMETRIE & INTELLIGENCE ARTIFICIELLE STN,F-31326 CASTANET TOLOSAN,FRANCE
[2] CIRAD,FLHOR,F-34032 MONTPELLIER 1,FRANCE
[3] CIMMYT,MEXICO CITY 06600,DF,MEXICO
[4] CIRAD,BIOTROP,F-34032 MONTPELLIER 1,FRANCE
关键词
GENETIC MAPPING; SEGREGATION DISTORTION; MAXIMUM-LIKELIHOOD; LINKAGE; MOLECULAR MARKERS;
D O I
10.1007/BF00220998
中图分类号
S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
A maximum-likelihood approach is used in order to estimate recombination fractions between markers showing segregation distortion in backcross populations. It is assumed that the distortions are induced by viability differences between gametes or zygotes due to one or more selected genes. We show that Bailey's (1949) estimate stays consistent and efficient under more general assumptions than those defined by its author. This estimate should therefore be used instead of the classical maximum-likelihood estimate. The question of detection of linkage is also discussed. We show that the order of markers on linkage groups may be affected by segregation distortion.
引用
收藏
页码:73 / 80
页数:8
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