POSSIBLE SHORT-TERM-MEMORY LOSS ASSOCIATED WITH NAFARELIN ACETATE

被引:7
作者
KORTEPETER, C
MACMILLAN, M
FERRELL, R
机构
[1] UNIV HAWAII,SCH NURSING,HONOLULU,HI 96822
[2] UNIV PACIFIC,SCH PHARM,STOCKTON,CA 95211
[3] MADIGAN ARMY MED CTR,TACOMA,WA 98431
关键词
D O I
10.1177/106002809202600203
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
OBJECTIVE AND DESIGN: A survey was conducted to determine the occurrence of short-term memory loss in patients using nafarelin acetate nasal spray. SETTING AND PATIENTS: A list of all patients receiving nafarelin acetate from our pharmacy over a four-month period was generated. We contacted and surveyed 16 women. INTERVENTIONS: Each patient was asked to repeat three words at the beginning of the survey and after a series of questions, each patient was asked to recall the three words. Patients were also asked if they believed that their memory was affected by nafarelin acetate nasal spray. RESULTS: Eleven patients (69 percent) recalled three words, 3 (19 percent) recalled two words, and 2 (13 percent) recalled one word at the conclusion of the survey. Nine of 16 patients (56 percent) reported some type of memory difficulty. CONCLUSIONS: Nafarelin acetate nasal spray may adversely affect short-term memory. This effect is not documented in current literature and further investigation is warranted in the possible relationship between gonadotropin releasing hormone agonists, estrogen deficiency, menopause, and short-term memory. Our survey also demonstrates the significance of communication between pharmacists and patients on newly marketed medications.
引用
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页码:169 / 171
页数:3
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