3-(2-CARBOXYINDOL-3-YL)PROPIONIC ACID-DERIVATIVES - ANTAGONISTS OF THE STRYCHNINE-INSENSITIVE GLYCINE RECEPTOR ASSOCIATED WITH THE N-METHYL-D-ASPARTATE RECEPTOR COMPLEX

被引：41

作者：

SALITURO, FG

HARRISON, BL

BARON, BM

NYCE, PL

STEWART, KT

MCDONALD, IA

机构：

[1] Merrell Dow Research Institute, Cincinnati Center, Ohio 45215

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1990年 / 33卷 / 11期

关键词：

D O I：

10.1021/jm00173a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：2944 / 2946

页数：3

共 15 条

[1]

BARON BM, 1989, J PHARMACOL EXP THER, V250, P162

[2]

BARON BM, UNPUB

[3] KYNURENATE AND FG9041 HAVE BOTH COMPETITIVE AND NON-COMPETITIVE ANTAGONIST ACTIONS AT EXCITATORY AMINO-ACID RECEPTORS [J].

BIRCH, PJ ;

GROSSMAN, CJ ;

HAYES, AG .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1988, 151 (02) :313-315

[4]

FOSTER AC, 1989, J NEUROSCI, V9, P2191

[5]

HARRISON B, UNPUB

[6]

HEUTTNER JE, 1989, SCIENCE, V243, P1611

[7] CHAOTROPIC IONS AFFECT THE CONFORMATION OF QUISQUALATE RECEPTORS IN RAT CORTICAL MEMBRANES [J].

HONORE, T ;

DREJER, J .

JOURNAL OF NEUROCHEMISTRY, 1988, 51 (02) :457-461

[8] GLYCINE POTENTIATES THE NMDA RESPONSE IN CULTURED MOUSE-BRAIN NEURONS [J].

JOHNSON, JW ;

ASCHER, P .

NATURE, 1987, 325 (6104) :529-531

[9] 7-CHLOROKYNURENIC ACID IS A SELECTIVE ANTAGONIST AT THE GLYCINE MODULATORY SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR COMPLEX [J].

KEMP, JA ;

FOSTER, AC ;

LEESON, PD ;

PRIESTLEY, T ;

TRIDGETT, R ;

IVERSEN, LL ;

WOODRUFF, GN .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (17) :6547-6550

[10] REQUIREMENT FOR GLYCINE IN ACTIVATION OF NMDA-RECEPTORS EXPRESSED IN XENOPUS OOCYTES [J].

KLECKNER, NW ;

DINGLEDINE, R .

SCIENCE, 1988, 241 (4867) :835-837

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