PROAZULENES FROM ACHILLEA-ASPLENIFOLIA

被引：9

作者：

KASTNER, U ^{[1
]}

JURENITSCH, J ^{[1
]}

GLASL, S ^{[1
]}

BAUMANN, A ^{[1
]}

ROBIEN, W ^{[1
]}

KUBELKA, W ^{[1
]}

机构：

[1] UNIV VIENNA,INST ORGAN CHEM,A-1090 VIENNA,AUSTRIA

来源：

PHYTOCHEMISTRY | 1992年 / 31卷 / 12期

关键词：

ACHILLEA-ASPLENIFOLIA; COMPOSITAE; GUAIANOLIDES; SESQUITERPENE LACTONES; PROAZULENES;

D O I：

10.1016/0031-9422(92)80478-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

From flower heads of Achillea asplenifolia Vent. the eight major proazulenes were isolated by repeated column chromatography and HPLC. By H-1 NMR and mass spectral studies, especially by measurements of NOE effects, four compounds were shown to be the first 7,8-guaianolide derivatives found in the Achillea millefolium group. They were identified as 4alpha-hydroxy-6alpha-angeloxy-9alpha-acetoxy-5alphaH,7alphaH,8betaH,11alphaH-guai-1(10),2-dien-7,8-olide and the respective 6alpha-tigloxy, 6alpha-acetoxy and 4-epi derivatives. One of the proazulenes was identified as 8-deacetyl-4-epi-matricin. The other three proazulenes represent the same 10-epi-artabsin derivatives as recently found in A. roseo-alba and A. collina, namely 8alpha-acetoxy-10-epi-artabsin (achillicin), 8alpha-angeloxy-10-epi-artabsin and 8alpha-tigloxy-10-epi-artabsin.

引用

页码：4361 / 4362

页数：2

共 9 条

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[8]

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[9]

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