ALDOL-TYPE REACTION OF ALPHA-HALO KETONES WITH ALPHA-KETOCARBOXYLATES MEDIATED BY SMI2 OR SMI3 - FACILE SYNTHESIS OF ALPHA-HYDROXY-GAMMA-KETOCARBOXYLATES

被引：9

作者：

ARIME, T ^{[1
]}

KATO, N ^{[1
]}

KOMADATE, F ^{[1
]}

SAEGUSA, H ^{[1
]}

MORI, N ^{[1
]}

机构：

[1] SCI UNIV TOKYO,DEPT CHEM,SHINJUKU KU,TOKYO 162,JAPAN

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 22期

关键词：

D O I：

10.1080/00397919408010255

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title reaction smoothly proceeds at room temperature to give alpha-hydroxy-gamma-keto esters 3 in good yields, probably via a mechanism involving samarium enolates formed in situ from alpha-halo ketones.

引用

页码：3315 / 3319

页数：5