EFFICACY, SAFETY, AND PHARMACOKINETICS OF A CONCENTRATION-MAINTAINING REGIMEN OF INTRAVENOUS PIRMENOL

被引：16

作者：

REITER, MJ

HAMMILL, SC

SHAND, DG

VERGHESE, C

MCCARTHY, E

PRITCHETT, ELC

机构：

[1] DUKE UNIV,MED CTR,DEPT MED,DIV CARDIOL,DURHAM,NC 27710

[2] DUKE UNIV,MED CTR,DEPT PHARMACOL,DIV CLIN PHARMACOL,DURHAM,NC 27710

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1983年 / 52卷 / 01期

关键词：

D O I：

10.1016/0002-9149(83)90074-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：83 / 87

页数：5

共 8 条

[1] PIRMENOL KINETICS AND EFFECTIVE ORAL DOSE [J].

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PRITCHETT, ELC .

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[2] PIRMENOL, A NEW ANTIARRHYTHMIC AGENT - INITIAL STUDY OF EFFICACY, SAFETY AND PHARMACOKINETICS [J].

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SHANDDG ;

ROUTLEDGE, PA ;

HINDMAN, MC ;

BAKER, JT ;

PRITCHETT, ELC .

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[3]

HASTINGS S, 1978, PHARMACOLOGIST, V20, P149

[4]

METZ TE, 1980, J CARDIOVASC PHARM, V2, P527

[5] HEMODYNAMIC-EFFECTS OF THE ANTIARRHYTHMIC DRUG PIRMENOL [J].

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LEE, KL ;

SHAND, DG ;

PRITCHETT, ELC .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1982, 32 (02) :235-239

[6] EFFECTS OF PIRMENOL HCL ON ELECTROPHYSIOLOGIC PROPERTIES OF CARDIAC PURKINJE-FIBERS [J].

REDER, RF ;

DANILO, P ;

ROSEN, MR .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1980, 61 (04) :321-333

[7] THE METHOD OF SEPARATE EXPONENTIALS - A SIMPLE AID TO DEVISING INTRAVENOUS DRUG-LOADING REGIMENS [J].

SHAND, DG ;

DESJARDINS, RE ;

BJORNSSON, TD ;

HAMMILL, SC ;

PRITCHETT, ELC .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 29 (04) :542-547

[8] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF A NEW ANTI-ARRHYTHMIC DRUG, PIRMENOL, IN BIOLOGICAL-FLUIDS [J].

SHAND, DG ;

VERGHESE, C ;

BARCHOWSKY, A ;

HAMMILL, SC ;

PRITCHETT, ELC .

JOURNAL OF CHROMATOGRAPHY, 1981, 224 (02) :343-347

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