CONTRASTING MODULATIONS OF GENE-EXPRESSION BY A JUVENILE-HORMONE ANALOG

被引：14

作者：

BRADFIELD, JY

BERLIN, RL

KEELEY, LL

机构：

[1] Laboratories for Invertebrate Neuroendocrine Research, Department of Entomology, Texas A and M University, College Station

来源：

INSECT BIOCHEMISTRY | 1990年 / 20卷 / 02期

基金：

美国国家科学基金会;

关键词：

cockroach; fat body; gene expression; juvenile hormone; molecular cloning;

D O I：

10.1016/0020-1790(90)90002-C

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Decapitation altered the pattern of in vitro protein synthesis by the fat body of adult female Blaberus discoidalis cockroaches. Several polypeptides showed marked diminution, whereas two polypeptides showed markedly increased synthesis. The polypeptide profile was restored to normal in decapitated cockroaches by treatment with the juvenile hormone analog (JHA) methoprene. Cloned cDNAs that were isolated represented two fat body transcripts: one transcript was strongly stimulated and the other strongly suppressed by JHA. JHA acted on fat bodies in vitro to modulate the levels of the two transcripts. These studies indicate a system where juvenile hormone may provoke vividly contrasting gene expressions in the same tissue at the same time. © 1990.

引用

页码：105 / 111

页数：7

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