EXTENSIVE MHC VARIABILITY IN CICHLID FISHES OF LAKE MALAWI

被引：127

作者：

KLEIN, D

ONO, H

OHUIGIN, C

VINCEK, V

GOLDSCHMIDT, T

KLEIN, J

机构：

[1] MAX PLANCK INST BIOL,IMMUNGENET ABT,W-7400 TUBINGEN,GERMANY

[2] LEIDEN UNIV,ZOOL LAB,ECOL MORPHOL RES GRP,2300 RA LEIDEN,NETHERLANDS

[3] YOKOHAMA CITY UNIV,SCH MED,DEPT DERMATOL,KANAZAWA KU,YOKOHAMA 236,JAPAN

来源：

NATURE | 1993年 / 364卷 / 6435期

关键词：

D O I：

10.1038/364330a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

LAKE Malawi in East Africa harbours 500-1,000 endemic species of cichlid fishes, all presumably derived by adaptive radiation from a single founding population within the past two million years1-3. The species of this 'flock' differ strikingly in their ecology and behaviour4, moderately in their external morphology1 and very little in their molecular characteristics5,6. Here we describe high sequence variability of class II major histocompatibility complex genes in a sample of species from Lake Malawi. The variability provides a set of molecular markers for studying adaptive radiation and should be useful for estimating the size of the population that founded the species flock.

引用

页码：330 / 334

页数：5

共 14 条

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[2] Fryer G., 1972, CICHLID FISHES GREAT
[3] FRYER GEOFFREY, 1959, PROC ZOOL SOC LONDON, V132, P153
[4] A SIMPLE METHOD FOR ESTIMATING EVOLUTIONARY RATES OF BASE SUBSTITUTIONS THROUGH COMPARATIVE STUDIES OF NUCLEOTIDE-SEQUENCES
KIMURA, M
[J]. JOURNAL OF MOLECULAR EVOLUTION, 1980, 16 (02) : 111 - 120
[5] KLEIN J, 1986, CRC CR REV IMMUNOL, V6, P295
[6] Klein J, 1986, NATURAL HIST MAJOR H
[7] Kornfield I., 1991, P103
[8] Lewis D., 1986, GUIDE FISHES LAKE MA
[9] MACKAYE KR, 1982, ZOOL J LINN SOC-LOND, V76, P91
[10] MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II GENES OF ZEBRAFISH
ONO, H
KLEIN, D
VINCEK, V
FIGUEROA, F
OHUIGIN, C
TICHY, H
KLEIN, J
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (24) : 11886 - 11890

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