APPLYING SIMULATION MODELING TO PROBLEMS IN TOXICOLOGY AND RISK ASSESSMENT - A SHORT PERSPECTIVE

被引：48

作者：

ANDERSEN, ME

CLEWELL, HJ

FREDERICK, CB

机构：

[1] ICF KAISER INT,KS CRUMP DIV,RUSTON,LA 71270

[2] ROHM & HAAS CO,DEPT TOXICOL,SPRING HOUSE,PA 19477

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1995年 / 133卷 / 02期

关键词：

D O I：

10.1006/taap.1995.1140

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

收藏

页码：181 / 187

页数：7

相关论文

共 26 条

[1] ADOLPH EF, 1947, SCIENCE, V109, P579
[2] Carson E R, 1983, MATH MODELING METABO
[3] Clewell H J 3rd, 1985, Toxicol Ind Health, V1, P111
[4] IMPROVING TOXICOLOGY TESTING PROTOCOLS USING COMPUTER-SIMULATIONS
CLEWELL, HJ
ANDERSEN, ME
[J]. TOXICOLOGY LETTERS, 1989, 49 (2-3) : 139 - 158
[5] BIOLOGICALLY MOTIVATED MODELS FOR CHEMICAL RISK ASSESSMENT
CLEWELL, HJ
ANDERSEN, ME
[J]. HEALTH PHYSICS, 1989, 57 : 129 - 137
[6] CONOLLY RB, 1988, COMMENTS TOXICOL, V2, P305
[7] ANIMAL SCALE-UP
DEDRICK, RL
[J]. JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1973, 1 (05): : 435 - 460
[8] PHYSIOLOGICAL PHARMACOKINETIC MODELS - SOME ASPECTS OF THEORY, PRACTICE AND POTENTIAL
DSOUZA, RW
BOXENBAUM, H
[J]. TOXICOLOGY AND INDUSTRIAL HEALTH, 1988, 4 (02) : 151 - 171
[9] PHYSIOLOGICAL MODEL FOR THE PHARMACOKINETICS OF METHYL MERCURY IN THE GROWING RAT
FARRIS, FF
DEDRICK, RL
ALLEN, PV
SMITH, JC
[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1993, 119 (01) : 74 - 90
[10] LIMITING THE UNCERTAINTY IN RISK ASSESSMENT BY THE DEVELOPMENT OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC AND PHARMACODYNAMIC MODELS
FREDERICK, CB
[J]. TOXICOLOGY LETTERS, 1993, 68 (1-2) : 159 - 175