1-CHLORO-2,2,2-TRIFLUOROETHYL RADICAL - FORMATION FROM HALOTHANE BY HUMAN CYTOCHROME-P-450 IN RECONSTITUTED VESICLES AND BINDING TO PHOSPHOLIPIDS

被引：37

作者：

TRUDELL, JR ^{[1
]}

BOSTERLING, B ^{[1
]}

TREVOR, A ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT PHARMACOL,SAN FRANCISCO,CA 94143

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1981年 / 102卷 / 01期

关键词：

D O I：

10.1016/0006-291X(81)91531-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：372 / 377

页数：6

共 12 条

[1]

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[2]

BOSTERLING B, 1980, MICROSOMES DRUG OXID, P115

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COHEN, EN ;

HOOD, N .

ANESTHESIOLOGY, 1969, 31 (06) :553-&

[4]

GANDOLFI AJ, 1980, J PHARMACOL EXP THER, V214, P721

[5] MECHANISM OF HALOTHANE BINDING TO MICROSOMAL CYTOCHROME P450 [J].

MANSUY, D ;

NASTAINCZYK, W ;

ULLRICH, V .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1974, 285 (04) :315-324

[6]

MUKAI S, 1975, ANESTHESIOLOGY, V47, P392

[7] EFFECT OF OXYGEN CONCENTRATION ON REACTION OF HALOTHANE WITH CYTOCHROME-P450 IN LIVER-MICROSOMES AND ISOLATED PERFUSED RAT-LIVER [J].

NASTAINCZYK, W ;

ULLRICH, V ;

SIES, H .

BIOCHEMICAL PHARMACOLOGY, 1978, 27 (04) :387-392

[8] VOLATILE METABOLITES AND DECOMPOSITION PRODUCTS OF HALOTHANE IN MAN [J].

SHARP, JH ;

TRUDELL, JR ;

COHEN, EN .

ANESTHESIOLOGY, 1979, 50 (01) :2-8

[9]

STIER A, 1968, ANESTHESIOLOGY, V29, P453

[10] APPARENT DEPENDENCE OF INTERACTIONS BETWEEN CYTOCHROME-B5 AND CYTOCHROME-B5 REDUCTASE UPON TRANSLATIONAL DIFFUSION IN DIMYRISTOYL LECITHIN LIPOSOMES [J].

STRITTMATTER, P ;

ROGERS, MJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (07) :2658-2661

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