DNA METHYLATION AND CHROMATIN STRUCTURE - A VIEW FROM BELOW

被引：156

作者：

SELKER, EU

机构：

[1] Institute of Molecular Biology, University of Oregon, Eugene

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 03期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/0968-0004(90)90193-F

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An understanding of the function and control of DNA methylation in eukaryotes has been elusive. Studies of Neurospora crassa have led to a model that accounts for the chromosomal distribution of methylation and suggests a basic function for DNA methylation in eukaryotes. © 1990.

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页码：103 / 107

页数：5

相关论文

共 30 条

[1]

[Anonymous], [No title captured]

[2] METHYLATED AND UNMETHYLATED DNA COMPARTMENTS IN THE SEA-URCHIN GENOME [J].

BIRD, AP ;

TAGGART, MH ;

SMITH, BA .

CELL, 1979, 17 (04) :889-901

[3] DNA METHYLATION AND THE FREQUENCY OF CPG IN ANIMAL DNA [J].

BIRD, AP .

NUCLEIC ACIDS RESEARCH, 1980, 8 (07) :1499-1504

[4] CPG-RICH ISLANDS AND THE FUNCTION OF DNA METHYLATION [J].

BIRD, AP .

NATURE, 1986, 321 (6067) :209-213

[5] HEAVILY METHYLATED AMPLIFIED DNA IN TRANSFORMANTS OF NEUROSPORA-CRASSA [J].

BULL, JH ;

WOOTTON, JC .

NATURE, 1984, 310 (5979) :701-704

[6] CHROMATIN STRUCTURE IS REQUIRED TO BLOCK TRANSCRIPTION OF THE METHYLATED HERPES-SIMPLEX VIRUS THYMIDINE KINASE GENE [J].

BUSCHHAUSEN, G ;

WITTIG, B ;

GRAESSMANN, M ;

GRAESSMANN, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (05) :1177-1181

[7] REPEAT-INDUCED G-C TO A-T MUTATIONS IN NEUROSPORA [J].

CAMBARERI, EB ;

JENSEN, BC ;

SCHABTACH, E ;

SELKER, EU .

SCIENCE, 1989, 244 (4912) :1571-1575

[8] DELAYED DENOVO METHYLATION IN TERATOCARCINOMA SUGGESTS ADDITIONAL TISSUE-SPECIFIC MECHANISMS FOR CONTROLLING GENE-EXPRESSION [J].

GAUTSCH, JW ;

WILSON, MC .

NATURE, 1983, 301 (5895) :32-37

[9]

GRAYBURN WS, 1989, MOL CELL BIOL, V9, P4409

[10] CYTOSINE METHYLATION DOES NOT AFFECT BINDING OF TRANSCRIPTION FACTOR-SP1 [J].

HARRINGTON, MA ;

JONES, PA ;

IMAGAWA, M ;

KARIN, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (07) :2066-2070