10 MORE RITTERAZINES, CYTOTOXIC STEROIDAL ALKALOIDS FROM THE TUNICATE RITTERELLA-TOKIOKA

被引:63
作者
FUKUZAWA, S [1 ]
MATSUNAGA, S [1 ]
FUSETANI, N [1 ]
机构
[1] UNIV TOKYO,FAC AGR,MARINE BIOCHEM LAB,BUNKYO KU,TOKYO 113,JAPAN
关键词
D O I
10.1016/0040-4020(95)00327-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Ritterazines D-M (4-13) have been isolated from the tunicate Ritterella tokioka and their structures elucidated by spectral data Ritterazines D-M showed potent cytotoxicity against P388 murine leukemia cells with IC50 values of 16, 3.5, 0.73, 0.73, 16, 14, 13, 9.5, 10, and 15 ng/mL, respectively.
引用
收藏
页码:6707 / 6716
页数:10
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