PRODUCTION OF RECOMBINANT PROTEINS IN SERUM-FREE MEDIA

被引：10

作者：

BRAOD, D

BORASTON, R

RHODES, M

机构：

[1] Celltech Ltd., Slough, SL1 4EN

来源：

CYTOTECHNOLOGY | 1991年 / 5卷 / 01期

关键词：

RECOMBINANT DNA; BIOPHARMACEUTICAL PROTEINS; PERFUSION CULTURE; FED-BATCH CULTURE; SERUM-FREE MEDIA;

D O I：

10.1007/BF00365533

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The advantages of serum-free culture for the manufacture of recombinant biopharmaceuticals from mammalian cells are reviewed. The process favoured is fed-batch serum-free cell culture. This process is applicable to the majority of cell lines, is practical on the large scale, gives the lowest manufacturing cost, and can be carried out without the use of any serum.

引用

页码：47 / 55

页数：9

共 24 条

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