COAGULASE-NEGATIVE STAPHYLOCOCCAL BACTEREMIA WITH SPECIAL REFERENCE TO SEPTIC SHOCK - EXPERIENCE IN AN INTENSIVE-CARE UNIT

被引:7
作者
DAHMASH, NS
CHOWDHURY, MNH
FAYED, DF
机构
[1] KING SAUD UNIV, KING KHALID UNIV HOSP, COLL MED, DEPT MED, RIYADH 11524, SAUDI ARABIA
[2] KING SAUD UNIV, KING KHALID UNIV HOSP, COLL MED, DEPT MICROBIOL, RIYADH 11524, SAUDI ARABIA
[3] KING SAUD UNIV, KING KHALID UNIV HOSP, COLL MED, DEPT PHARM, RIYADH 11524, SAUDI ARABIA
关键词
D O I
10.1016/S0163-4453(94)91220-3
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
During a period of 4.5 years, 48 patients with bacteraemia due to coagulase-negative staphylococci were studied prospectively in order to evaluate their clinical profile, management and outcome. There were 25 males and 23 females with ages ranging between 13 and 100 years. Over 60 % of patients belonged to the age group 30 to 69 years. Shock was recorded in 23 (48 %) of the 48 patients. Of the shocked patients, 16 were immunocompromised and also had abnormal coagulation. Their mortality was 44% By contrast, none of the immunocompromised patients without shock died. Abnormal coagulation was found in 17 patients without septic shock. Their mortality was 5.9% The commonest underlying disease was respiratory failure especially in shocked patients. The source of infection was identified in the majority of cases. In addition, most patients had an indwelling intravascular catheter especially an arterial one. The overall mortality was 16.7 % (8/48). It was significantly higher in patients with shock than in those without shock (30.4 % vs 4.0 %, P < 0.05).
引用
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页码:295 / 303
页数:9
相关论文
共 26 条
[1]  
BALK RA, 1989, CRIT CARE CLIN, V5, P1
[2]   INFECTIONS CAUSED BY ARTERIAL CATHETERS USED FOR HEMODYNAMIC MONITORING [J].
BAND, JD ;
MAKI, DG .
AMERICAN JOURNAL OF MEDICINE, 1979, 67 (05) :735-741
[3]  
BURCHARD KW, 1984, ARCH SURG-CHICAGO, V119, P96
[4]  
CHOWDHURY MNH, 1981, SAUDI MED J, V2, P225
[5]   QUANTITATIVE CULTURE OF INTRAVENOUS CATHETERS AND OTHER INTRAVASCULAR INSERTS [J].
CLERI, DJ ;
CORRADO, ML ;
SELIGMAN, SJ .
JOURNAL OF INFECTIOUS DISEASES, 1980, 141 (06) :781-787
[6]   SEPTIC SHOCK IN CRITICALLY ILL PATIENTS - ETIOLOGY, MANAGEMENT AND OUTCOME [J].
DAHMASH, NS ;
CHOWDHURY, MNH ;
FAYED, DF .
JOURNAL OF INFECTION, 1993, 26 (02) :159-170
[7]  
DAHMASH NS, 1993, MED SCI RES, V21, P409
[8]  
DAHMASH NS, 1993, MED SCI RES, V21, P207
[9]   HOSPITAL-ACQUIRED BLOOD-STREAM INFECTIONS WITH STAPHYLOCOCCUS EPIDERMIDIS - REVIEW OF 100 CASES [J].
DELEON, SP ;
WENZEL, RP .
AMERICAN JOURNAL OF MEDICINE, 1984, 77 (04) :639-644
[10]   NEONATAL INTENSIVE-CARE UNIT BACTEREMIA - EMERGENCE OF GRAM-POSITIVE BACTERIA AS MAJOR PATHOGENS [J].
DONOWITZ, LG ;
HALEY, CE ;
GREGORY, WW ;
WENZEL, RP .
AMERICAN JOURNAL OF INFECTION CONTROL, 1987, 15 (04) :141-147