THE INTERFERON-INDUCIBLE, DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE-DEAMINASE GENE (DSRAD) MAPS TO HUMAN-CHROMOSOME LQ21.1-21.2

被引：61

作者：

WEIER, HUG

GEORGE, CX

GREULICH, KM

SAMUEL, CE

机构：

[1] UNIV CALIF SANTA BARBARA, DEPT MOLEC CELLULAR & DEV BIOL, BIOCHEM & MOLEC BIOL PROGRAM, SANTA BARBARA, CA 93106 USA

[2] UNIV CALIF BERKELEY, LAWRENCE BERKELEY LAB, DIV LIFE SCI, CTR MOLEC CYTOGENET, BERKELEY, CA 94720 USA

[3] UNIV CALIF SANTA BARBARA, GRAD PROGRAM BIOCHEM & MOLEC BIOL, SANTA BARBARA, CA 93106 USA

来源：

GENOMICS | 1995年 / 30卷 / 02期

关键词：

D O I：

10.1006/geno.1995.0034

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The interferon-inducible double-stranded RNA-specific adenosine deaminase is an RNA-modifying enzyme implicated in the generation of biased hypermutations of viral RNAs and the site-selective editing of mammalian mRNAs of neural origin. The gene for the dsRNA-specific adenosine deaminase has been mapped by fluorescence in situ hybridization (FISH) of genomic clones to a single locus on human chromosome 1 bands q21.1-21.2. Simultaneous multicolor FISH including lambda clones and yeast artificial chromosomes showed a localization of the gene in band 1q21 centromeric of D1S1705. (C) 1995 Academic Press, Inc.

引用

页码：372 / 375

页数：4

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