THE ANTIINFLAMMATORY EFFECTS OF CHINESE CRUDE DRUG PRESCRIPTIONS ON EXPERIMENTAL ARTHRITIS

被引：3

作者：

LIN, CC

CHEN, MF

CHEN, CF

机构：

[1] School of Pharmacy, Kaohsiung Medical College

来源：

AMERICAN JOURNAL OF CHINESE MEDICINE | 1995年 / 23卷 / 02期

关键词：

D O I：

10.1142/S0192415X95000195

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

San-Miao-Warn (SMW), Tuhwo-Jih-Shen-Tang (TJS) and Dang-Quei-Nian-Tong-Tang (DGT) are Chinese traditional prescriptions. In this study, we evaluated the anti-inflammatory activities of these crude drug prescriptions in carrageenan-induced acute arthritis and complete Freund's adjuvant (CFA)-induced chronic arthritis in rats. It was found that pretreatment with SMW, TJS or DGT at a dosage of 100 mg/kg or 300 mg/kg, significantly inhibited carrageenan-induced acute arthritis. Moreover, these crude drugs also significantly suppressed the development of chronic arthritis induced by CFA. These results suggest that SMW, TJS and DGT are potential anti-inflammatory agents and may be considered as alternatives for non-steroid anti-inflammatory drugs (NSAID).

引用

页码：145 / 152

页数：8