DETECTION AND ASSIGNMENT OF THE GLUCOSE SIGNAL IN H-1-NMR DIFFERENCE SPECTRA OF THE HUMAN BRAIN

被引：44

作者：

GRUETTER, R

ROTHMAN, DL

NOVOTNY, EJ

SHULMAN, GI

PRICHARD, JW

SHULMAN, RG

机构：

[1] YALE UNIV,DEPT INTERNAL MED,NEW HAVEN,CT 06510

[2] YALE UNIV,DEPT NEUROL,NEW HAVEN,CT 06510

[3] YALE UNIV,DEPT PEDIAT,NEW HAVEN,CT 06510

来源：

MAGNETIC RESONANCE IN MEDICINE | 1992年 / 27卷 / 01期

关键词：

D O I：

10.1002/mrm.1910270118

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The difference between 1H NMR spectra obtained during eu‐ and hyperglycemia exhibited well‐resolved glucose peaks between 3 and 4 ppm as demonstrated by comparison with solution spectra. Estimated increases were consistent with recent 13C NMR quantitations of intracerebral glucose. Difference spectra were measured in 36‐ml volumes from the human brain every 3 min. Copyright © 1992 Wiley‐Liss, Inc., A Wiley Company

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页码：183 / 188

页数：6

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