SUPRACHIASMATIC LESIONS ELIMINATE 24-H BLOOD-PRESSURE VARIABILITY IN RATS

被引：64

作者：

JANSSEN, BJA ^{[1
]}

TYSSEN, CM ^{[1
]}

DUINDAM, H ^{[1
]}

RIETVELD, WJ ^{[1
]}

机构：

[1] LEIDEN UNIV,DEPT PHYSIOL,LEIDEN,NETHERLANDS

来源：

PHYSIOLOGY & BEHAVIOR | 1994年 / 55卷 / 02期

关键词：

BLOOD PRESSURE; HEART RATE; VARIABILITY; SCN; CIRCADIAN RHYTHMICITY; RATS;

D O I：

10.1016/0031-9384(94)90138-4

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

To evaluate whether the suprachiasmatic nuclei (SCN) control 24-h rhythmicity in cardiovascular function, rats were subjected to computerized recording of 24-h blood pressure (BP) and heart rate (HR) following SCN lesions. In sham- and nonlesioned rats, circadian patterns of BP and HR ran in phase with those in feeding behavior. In SCN-lesioned rats circadian rhythmicity in BP, HR and food intake were abolished. Minute-to-minute variation of BP and HR was similar as in sham- and nonlesioned rats. We conclude that long-term but not short-term variability of blood pressure and heart rate is largely determined by SCN-controlled activity levels.

引用

页码：307 / 311

页数：5

共 16 条

[1] CIRCADIAN-RHYTHM OF BLOOD-PRESSURE - INTERNAL AND EXTERNAL TIME TRIGGERS [J].