ANTIGENIC AND GENETIC ANALYSES OF INFLUENZA TYPE-B VIRUSES ISOLATED IN RUSSIA, 1987-91

被引：7

作者：

HEMPHILL, ML ^{[1
]}

ROTA, PA ^{[1
]}

IVANOVA, VT ^{[1
]}

SLEPUSHKIN, AN ^{[1
]}

KENDAL, AP ^{[1
]}

机构：

[1] DI IVANOVSKII INST VIROL,MOSCOW 123098,RUSSIA

来源：

EPIDEMIOLOGY AND INFECTION | 1993年 / 111卷 / 03期

关键词：

D O I：

10.1017/S0950268800057265

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Four influenza type B viruses isolated in Russia during periods of relatively low (1987-8) or high (1990-1) influenza B activity were characterized antigenically using a microneutralization assay. These isolates were antigenically similar to contemporary reference strains from either of two separate lineages represented by B/Victoria/2/87 and B/Yamagata/16/88. The evolutionary relationships of the variable portion of the haemagglutinin (HA1) genes of these viruses were determined by comparison with influenza B HA1 sequences previously obtained. The Isolate B/USSR/2/87, collected during the 1987-8 influenza season, was found to be closely related to viruses on the B/Victoria/2/87 lineage that circulated during the 1988-9 influenza season in the United States. Sequence analysis of the isolates from the 1990-1 influenza season demonstrated co-circulation of viruses from both the B/Victoria/2/87 and B/Yamagata/16/88 lineages in Russia, confirming the antigenic analysis.

引用

页码：539 / 546

页数：8

共 23 条

[1]

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