PROTEIN HISTIDINE KINASES AND SIGNAL-TRANSDUCTION IN PROKARYOTES AND EUKARYOTES

被引：196

作者：

ALEX, LA

SIMON, MI

机构：

[1] L.A. Alex and M.I. Simon are in the California Institute of Technology, Pasadena

来源：

TRENDS IN GENETICS | 1994年 / 10卷 / 04期

关键词：

D O I：

10.1016/0168-9525(94)90215-1

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

During the past several years, it has become apparent that prokaryotic organisms process much of their sensory information through families of similar proteins that make up two-component signal transducing systems. Biochemical and genetic analyses have clarified our understanding of how these proteins mediate the signaling circuitry necessary to allow an appropriate response. Recent advances in this field suggest that 'primitive' signaling systems may involve molecular strategies and mechanisms that are conserved in more complex organisms.

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页码：133 / 138

页数：6

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