INCORPORATION OF H2O-18 INTO 20ALPHA, 22R-DI-OH CHOLESTEROL - EVIDENCE FOR AN EPOXIDE-DIOL PATHWAY IN ADRENOCORTICAL CHOLESTEROL SIDE-CHAIN CLEAVAGE MECHANISM

被引：26

作者：

KRAAIPOEL, RJ

DEGENHART, HJ

LEFERINK, JG

机构：

[1] ERASMUS UNIV,DEPT PEDIAT,ROTTERDAM,NETHERLANDS

[2] ACAD HOSP ROTTERDAM,ROTTERDAM,NETHERLANDS

[3] SOPHIA CHILDRENS HOSP,NEONATAL UNIT,GORDELWEG 160,ROTTERDAM,NETHERLANDS

[4] STATE UNIV UTRECHT,LAB TOXICOL,UTRECHT,NETHERLANDS

来源：

FEBS LETTERS | 1975年 / 57卷 / 03期

关键词：

D O I：

10.1016/0014-5793(75)80320-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：294 / 300

页数：7

共 18 条

[1]

BURSTEIN S, 1975, FED PROC, V34, P660

[2] ENZYMATIC FORMATION OF (20R,22R)-20,22-DIHYDROXYCHOLESTEROL FROM CHOLESTEROL AND A MIXTURE OF O-16(2) AND O-18(2) - RANDOM INCORPORATION OF OXYGEN-ATOMS [J].

BURSTEIN, S ;

MIDDLEDITCH, BS ;

GUT, M .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1974, 61 (02) :692-697

[3] TRANSFORMATION OF LABELED CHOLESTEROL, 20ALPHA-HYDROXYCHOLESTEROL, (22R)-22-HYDROXYCHOLES-TEROL, AND (22R)-20ALPHA, 22-DIHYDROXYCHOLESTEROL BY ADRENAL ACETONE-DRIED PREPARATIONS FROM GUINEA PIGS, CATTLE AND MAN .2. KINETIC STUDIES [J].

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[4]

CHAUDHURI AC, 1962, J BIOL CHEM, V237, P703

[5] CLEAVAGE OF CHOLESTEROL SIDE CHAIN BY ADRENAL CORTEX .3. IDENTIFICATION OF 20 ALPHA-22 XI-DIHYDROXYCHOLESTEROL AS AN INTERMEDIATE [J].

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TCHEN, TT .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1962, 8 (1-2) :50-&

[6] INHIBITION OF BIOSYNTHESIS OF PREGNENOLONE BY 20ALPHA-HYDROXYCHOLESTEROL [J].

HALL, PF ;

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[7]

HOCHBERG RB, 1974, J BIOL CHEM, V249, P1277

[8]

KRAAIPOEL RJ, 1974, ACTA PAEDIATR SCAND, V63, P333

[9] PREGNENOLONE FORMATION FROM CHOLESTEROL IN BOVINE ADRENAL-CORTEX MITOCHONDRIA - PROPOSAL OF A NEW MECHANISM [J].

KRAAIPOEL, RJ ;

DEGENHART, HJ ;

LEFERINK, JG ;

VANBEEK, V ;

DELEEUWBOON, H ;

VISSER, HKA .

FEBS LETTERS, 1975, 50 (02) :204-209

[10] EVIDENCE FOR 20, 22-EPOXYCHOLESTEROL AS AN INTERMEDIATE IN SIDE-CHAIN CLEAVAGE OF 22R-OH CHOLESTEROL BY ADRENAL-CORTEX MITOCHONDRIA [J].

KRAAIPOEL, RJ ;

DEGENHART, HJ ;

VANBEEK, V ;

LEEUWBOON, HD ;

ABELN, G ;

VISSER, HKA ;

LEFERINK, JG .

FEBS LETTERS, 1975, 54 (02) :172-179

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