AMINOTHIADIAZOLE (NSC 4728) IN PATIENTS WITH ADVANCED-CARCINOMA OF THE ENDOMETRIUM - A PHASE-II STUDY OF THE GYNECOLOGIC-ONCOLOGY-GROUP

被引：21

作者：

ASBURY, RF

BLESSING, JA

MCGUIRE, WP

HANJANI, P

MORTEL, R

机构：

[1] UNIV ROCHESTER,GENESSEE HOSP,SCH MED,ROCHESTER,NY 14607

[2] NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,GYNECOL ONCOL GRP,BUFFALO,NY 14263

[3] JOHNS HOPKINS UNIV HOSP,CTR ONCOL,BALTIMORE,MD 21205

[4] TEMPLE UNIV,HLTH SCI CTR,PELV ONCOL SECT,PHILADELPHIA,PA 19140

[5] PENN STATE UNIV,MILTON S HERSHEY MED CTR,DEPT OBSTET & GYNECOL,HERSHEY,PA 17033

来源：

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS | 1990年 / 13卷 / 01期

关键词：

D O I：

10.1097/00000421-199002000-00011

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Twenty-one evaluable patients with advanced carcinoma of the endometrium were treated with aminothiadiazole at a dosage of 125 mg/m2 weekly. Twelve had received prior chemotherapy. Seven patients had stable disease; 14 had increasing disease. There were two life-threatening toxic episodes. Aminothiadiazole used in this dosage and schedule has negligible activity in previously treated patients with carcinoma of the endometrium.

引用

页码：39 / 41

页数：3

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